Thammudu is action romance based movie in which, Janaki and Subhash are neighbors, who are friends from childhood. They move around very closely. Subhash is a freak-out guy and Janaki cares for him a lot. Chakri is Subhash elder brother, who is very responsible and on the way to fulfill his father’s dream of becoming a kickboxing champion.
There is an age long rivalry between Model School and Govt. School in that town. Chakri, Subhash and Janaki belong to Govt. School. Rich and spoilt teenage boppers dominate the Model School. Bhupender is the gang leader of Model school and is hunted by Modern gals.
Subhash father settles the match for Chakri with Chakri’s longtime flame. As Chakri was going to get his brother home for his engagement, he was beaten up by Bhupendar and other model school guys. Chakri is so badly injured that he needs the bed rest for 3 months. In this process his father’s irritation towards Subhash multiplies.
Subhash approaches the guru of chakri to learn the art of kickboxing rest of the story is about how Subhash fullfil his father's goal.