Raghavendra is an Action based movie. In which, Raghava is a hot blooded and restless youth who cant tolerate injustice that is being done in the society. In the process, he picks up fight with local mafia leader Ankineedu (Anandraj). Ankineedu stabs Sirisha the ladylove of Raghava to death. He also issues ultimatum to the parents of Raghava to leave the city in few hours. The vexed parents ask Raghava to accompany them only if he agrees to listen to their words. They take Raghava to Mantralayam - a relatives place and make him become a devotee of Lord Raghavendra Swamy.
This entire episode comes as flashback. Raghava has a pretty sister-in-law called Maha Lakshmi (Swetha Agarwal) in Mantralayam. Raghava becomes a saint-like-man and does not even respond when some goons humiliate Maha Lakshmi. He does not bother to retaliate even when goons strip Maha Lakshmi off of her cloths in public.
The parents of Raghava who forcibly restricted the helping nature of Raghava ask Raghava to get rid of his maala and go back to society to serve people. The rest of the story is about how Raghava puts ends to Ankineedu.