Premikulu is romantic based movie in which, Chandu (Yuvaraj) and Vennela (Kamna Jetmalani) fall in love. But parents reject their love.
With no other option left, they attempt suicide by jumping from the top floor of a building. Luckily, they were saved as they fall in sand. But, they suffer memory loss. The doctors term this disorder as 'retrograde amnesia' (brain injury in which the individual loses memories for the time period just prior to the injury (depends on few minutes to several years)).
The rest of the story is all about how they get united again though technically they do not know each other.