Lahiri Lahiri Lahirilo is afamily drama based movie in which, Nani (Aditya) is an orphan and a fun loving college student. He makes his living by acting as a marriage broker. He gets a proposal to find matches to three sisters namely Indu (Bhanu Priya), Chandu (Rachana) and Sindhu (Sanghvi). But their father is adamant that his daughters should get married to three brothers. Nani discovers that there is a set of three unmarried brothers in a village. Nani converts himself as the younger brother of these three sisters and visits the village of three brothers on the eve of a festival. These visitors are put up in a house, which is just apposite to that of those three brothers, namely Krishnama Naidu (Hari Krishna), Chandrama Naidu (Suman) and Sreenivasa Naidu (Vineeth).
These three brothers have a pretty younger sister named Priya (Ankita). Priya and Nani are classmates back in the city college. Both of them love each other, but never express it. Nani starts playing the role of cupid for the three brothers and three sisters. That village has a rule that the brothers cannot marry unless the sister in the house is married. That's why these three brothers remain unmarried even after they entered 30's, as their sister is not ready for the marriage.
There is a woman called Achamamba (Lakshmi), who once loved Raghava Naidu (K Viswanath), the father of three brothers. But due to some circumstances, he marries another lady. Hence Achamamba remains as a spinster and vows to create havoc in the lives of Raghava Naidu and his sons. rest of the story is about how Nani manages to get all togather with his marriage.