Eeswar is a romance based movie in which, Eeswar (Prabhas) is a motherless child and brat living in Dhoolpet, a slum area in Old City. Eeswar's father manufactures Gudumba (arrack) with the help of neighborhood people. Eeswar falls in love at first sight when he sees a college going beauty Indu (Sridevi). In the meantime, Eeswar's father marries Sujatha (Revathi), who has been waiting for him for the past 20 years so that she can be a good mother to Eeswar. Eeswar hates his stepmother thinking that his father married her to enjoy worldly pleasures.
Meanwhile, Indu's father turns out to be a local MLA who hates poor. Local MLA sends goons to Eeswar to finish him off. rest of the story is about how Eeswar escapes from these goons and marry Indu with help of his friends.