Annayya movie is about Rajaram (Chiranjeevi), owner of a fleet of lorries, meets Devi (Soundarya), the garment factory owner. After that acquaintance, she once seeks his help in dealing with two street ruffians, who were teasing her sisters, Lata and Geeta.
Once she is shocked when the culprits turn out to be his brothers, Ravi (Ravi Teja) and Gopi (Venkat). Rajaram takes the incident lightly as the pranks of youngsters and is very lenient to them. With more such incidents the two come together and fall in love, with the brothers and sisters not far behind.
On his brothers request Rajaram approaches Devi for her sisters' hand in marriage to his brothers. But she curtly refuses her consent on grounds that the two are wayward drunkards. Rajaram reacts sharply to it and vows to get his brothers married to her sisters.
Rest of the story is about how Rajaram helps his brother's indirectly to achive their goals.