Guru En Aalu revolves around three characters - Madhavan, Mamta Mohandas and Abbas.
Madhavan is a result-oriented young man, passionately dedicated to achieving his goal in life. In addition to his qualifications, skills and attitude, Madhavan wants to apply his extra smartness to grab a favourable opportunity to settle in life.
Modern Miss Mamta Mohandas too is ambitious, focussed and full of vim and vigour. Mamta too is ready to put in a bit of her charm and skills to move up the corporate ladder. Both embark upon a job hunt. Predictably, both these likeminded individuals meet. When, where and with what result? Both get jobs in a prominent company and begin to like others company. Soon, their fledgling romance gets interrupted.
Abbas, the MD of the company has a clandestine weakness for pretty women and soon falls for gorgeous Mamta. Mamta, who was initially reluctant, subsequently accepts his advances, calculating the prospective benefits. The situation becomes too gauche to handle when Abbas chooses Madhavan to be the ambassador for his affair. But using Abbas as an tool, Madhavan and Mamta join forces and make wise plans to move to the top.