Pandipada movie tells the story of Bhuvanachandran (Dileep) and Bhasi (Harishree Ashokan) who are friends. All the ventures they started were a flop. Every failure leads to the next project. Bhuvanachandran ran away from his town leaving Bhasi behind. Bhasi did the same too.
Bhuvanachandran reached a village named "Karuvelikattil" in Tamil Nadu. Agriculture was main trade there. they decided to do farming and lead a good life.
Karuppayya and Pandidurey are the chieftains on the village. Pandidurey has an army of young thugs nick named "Pandippada", a nightmare for the whole village. Bhuvanachandran and Bhasi become the favorites of both Karuppayya and Pandidurey in short time.
Trouble starts when Bhuvanachandran met Meena, daughter of Karuppayya. They fall in love. Bhuvanchandran is so sure that he will be killed whether by Karuppayya or Pandidurey; he decides to run for his life.