Harindran Oru Nishkalangan movie is all about Hareendran (Manikuttan) who is born rich, but independently sets up a software company with turnover running into crores. He has a friend Gopalakrishnan aka GK (Jayasurya) who stays and works with him. GK is fleecing him, but Hareendran does not seem to care because he treats GK like a brother.
GK has other plans too. He wants to be the Executive Director of the company and ultimately own the company. For this purpose, he implements a scheme, which leads to his murder. Hareendran is the first accused for the murder. The court acquits him due to lack of evidence, but the media and the general public has already decided that he is the murderer.