Aayushkalam movie revolves around Balakrishnan (Mukesh) who is sick and has a heart disease, gets a heart transplant from a man Aby Mathew (Jayaram) who died in a recent car accident. The operation is a success but, Balakrishnan starts seeing the ghost of Aby, who lingers around for Balakrishnan to help him find his murderer so that his soul can rest in peace.
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