Life as We Know It is an upcoming 2010 comedy film directed by Greg Berlanti. The movie telling two single adults (Heigl and Duhamel) become caregivers to an orphaned girl when their mutual best friends die in a car accident.
Holly Berenson is an up-and-coming caterer and Eric Messer is a promising network sports director. After a disastrous first date, the only thing they have in common is their dislike for each other and their love for their goddaughter, Sophie. But when they suddenly become all Sophie has in the world, Holly and Messer are forced to put their differences aside. Juggling career ambitions and competing social calendars, they'll have to find some common ground while living under one roof.