Meghna was born in the Naidu family in Vijayawada, Andhra Pradesh, India.
She shot into fame with a video titled 'Kaliyon Ka Chaman', and instantly became popular as an 'item girl' in Bollywood.
Although she debuted in movies in Southern India in the Tamil language, she made her Bollywood presence in 'Hawas' during the year 2004. Since then she has acted in 11 more movies. As of September, 2007, she is also slated to act in Telugu and Malyalam language movies, including one titled 'Chandrika', and hopes to shed off her glamorized image in Ashok Nanda's movie titled 'Riwaaz'.