In Ankert University, California, Alisha (Priyanka Chopra) is the name of that dream everyone wished came true. The most beautiful girl on campus, she makes hearts flutter like leaves in the wind. A snap of her fingers and a line of boys, waiting on her every whim. Everybody Loves Alisha!

It is no surprise then that Abhay (Uday Chopra) loves her too. More than his computer programs and MAC stores he thinks of Alisha. Who is Abhay? Abhay is a nerdy, awkward, socially challenged, bespectacled geek of the college who is so far removed from her world that she doesn't even know that people like him actually exist.

This is a love story of impossible proportions, how can a man like Abhay ever hope to be with a woman like Alisha, and therein lies the story...

Abhay has quietly loved Alisha all his life. One day he musters up enough courage to go and express his true feelings to her and realizes that it is never gonna happen. He comes to terms with the fact that Alisha is a Princess and he is just a Geek. That is when their ways eventually part. Later, their paths cross again, as Abhay is busy trying to launch his career. Fate again brings him face to face with the woman of his dreams, Alisha.

Will Abhay have the strength to believe in himself and attempt to achieve what he never thought possible? Will Alisha ever be able to see the man behind those glasses, beyond what her idea of the perfect man is? Is everything fate or can one take destiny in their own hands? Is this possible or just Pyaar Impossible?