Masti films is about three married men Vivek Oberoi, Aftab Shivdasani and Ritesh Deshmukh who want to escape their wives Amrita Rao, Tara Sharma, and Genelia D'Souza by reliving their fun bachelor days. In the film, one of the wives tortures her husband, the next one repeatedly practices puja for her husband, and the last one is obsessed with hers.
The three men set their sights on other women, but eventually realize they have all been seeing the same girl Lara Dutta. She blackmails them but is found dead in a car the next day. A hilarious cat-and-mouse game between the three men and a suspicious police officer Ajay Devgan follows. In the end, they find out this was a trick played on them by their wives.