Lakeer is the story of detailing the subtle nuances of human interactions. Arjun Rana (Sunny Deol) is a powerful personality, feared by all. The apple of his eye is his brother Karan (Sohail Khan), who uses his brother's rich and famous image to the maximum advantage and always procures what he desires.
On the other hand, Sanju (Suniel Shetty) is a motor mechanic, loved by all. He idolizes Arjun Rana and wants to become like him. His love for his brother Saahil (John Abraham) is absolutely unshakable. Saahil represents the youth of the college and is in love with Bindiya (Nauheed Cyrusi). And, Bindiya happens to be Arjun Rana's sister. Traditional rivals arise when Karan also falls in love with Bindiya and the two gangs started to get blood shed conflicts in broad day light, which may lead to a dead end.